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    583-55-1

    Catalog No. EBD3596

    CAS 583-55-1

    Name 1-Bromo-2-iodobenzene

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    Basic Information

    Synonyms: Dipotassiumoxalate 1-Bromo-2-iodobenzene 2-bromoiodobenzene O-bromoiodobenzenem o-bromoiodobenzene 1-bromo-2-oiodobenzene 2-bromoindan-1-one benzene,1-bromo-2-iodo- 2-iodobromobenzene -bromo-2-iodobenzene 1-brom-2-iodobenzene 2-bromophenyliodide 1-bromo-2-iodo-benzen 1-iodo-2-bromobenzene

    Molecular Formula: C6H4BrI

    Molecular Weight: 282.9

    MDL Number: MFCD00001030

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Materials Chemistry > Optoelectronic and Organic Semiconductor Materials > OLED and Organic Optoelectronic Precursors

    Product Description:
    1-Bromo-2-iodobenzene is a bifunctional aromatic building block featuring both bromine and iodine substituents in an ortho relationship. The iodine atom is significantly more reactive than bromine in oxidative addition reactions, enabling selective cross-coupling transformations such as Sonogashira, Suzuki-Miyaura, or Buchwald-Hartwig reactions at the iodine site while leaving the bromine intact for subsequent functionalization. This ortho-dihalobenzene is widely employed in the synthesis of polycyclic aromatic hydrocarbons, heterocycles, and ligands for metal complexes. It is also utilized as a precursor in the preparation of pharmaceuticals, agrochemicals, and advanced materials, particularly where sequential or orthogonal coupling strategies are required. The compound is typically a colorless to light yellow liquid, sensitive to light, and should be stored under inert atmosphere to prevent decomposition.
    Physical Properties

    Melting Point: 9-10 °C(lit.)

    Boiling Point: 120-121 °C/15 mmHg(lit.)

    Flash Point: 113 °C

    Density: 2.203 g/mL at 25 °C(lit.)

    Refractivity: n20/D 1.661(lit.)

    Analytical Data

    Appearance: light yellow to red liquid

    mg g kg ml l t