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    576-23-8

    Catalog No. EBD13194

    CAS 576-23-8

    Name 3-Bromo-1,2-dimethylbenzene

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    Basic Information

    Synonyms: 3-Bromo-1,2-dimethylbenzene 3-Bromo-o-xylene 2,3-Dimethylbromobenzene 3-bromo-ortho-xylene 1-BROMO-2,3-DIMETHYLBENZENE 2,3-benzene,methylbromide

    Molecular Formula: C8H9Br

    Molecular Weight: 185.06

    MDL Number: MFCD00000069

    Product Description:
    3-Bromo-1,2-dimethylbenzene is a halogenated aromatic compound featuring a bromine atom at the 3-position and two methyl groups at the 1- and 2-positions on a benzene ring. It is a key synthetic building block widely used in organic synthesis, particularly in cross-coupling reactions such as Suzuki, Heck, and Buchwald-Hartwig aminations to construct complex molecular architectures. As a versatile intermediate, it serves as a precursor in the pharmaceutical industry for the synthesis of small-molecule drug fragments, including potential candidates targeting neurological and inflammatory pathways. Its bromine substituent provides a reactive handle for further functionalization, while the dimethyl substitution pattern influences steric and electronic properties, making it valuable for developing novel therapeutic agents. This compound is typically handled under standard laboratory conditions with appropriate safety measures due to its irritant properties. It is commercially available and commonly employed in medicinal chemistry research and material science applications.
    Physical Properties

    Boiling Point: 214 °C(lit.)

    Flash Point: 80 °C

    Density: 1.365 g/mL at 25 °C(lit.)

    Refractivity: n20/D 1.560(lit.)

    Safety Information

    Packing Level: III

    Hazard Category: /

    Transport Codes: 1993

    Analytical Data

    Appearance: Clear colourless to light yellow liquid

    mg g kg ml l t