Gabexate mesylate, CAS No. 56974-61-9

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56974-61-9

Catalog No. EBD15250

CAS 56974-61-9

Name Gabexate mesylate

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Basic Information

Synonyms: gabexatemesylate 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxyl]benzoicacidethylestermesylatesalt megacart Gabexate Mesylate p-Hydroxybenzoicacidethylester6-guanidinohexanoatemesilate Ethylp-(6-guanidinohexanoxyloxy)benzoatemethanesulfonate Benzoicacid,4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-,ethylester,monomethanesulfonate FOY007 Arodate(TN) [N-[5-(4-ethoxycarbonylphenoxy)carbonylpentyl]carbamimidoyl]azanium methanesulfonate Benzoicacid,4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-,ethylester,monomethanesulfonate Ethylp-hydroxybenzoate6-guanidinohexanoate 39492-01-8 Gabexatemesilate(JP14) Gabexatemesilate FOY FOY-S983 Gabexatemonomethanesulfonate Gabexatum[INN-Latin] Gabexato[INN-Spanish] Gabexatomesilato[Spanish] Ethylp-(6-guanidinohexanoyloxy)benzoatemethanesulfonate 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxyl)benzoicacidethylestermesylatesalt Gabex

Molecular Formula: C17H27N3O7S

Molecular Weight: 417.48

MDL Number: MFCD00210299

Categories: Medicinal Chemistry > APIs and Their Salts > Digestive System Drugs Medicinal Chemistry > Drug Impurities and Reference Standards > Impurity Standards

Product Description:

Gabexate mesylate is a synthetic serine protease inhibitor. Chemically, it is the methanesulfonate salt of gabexate, which is an ester derivative of 6-guanidinohexanoic acid and 4-hydroxybenzoic acid. It is a white to off-white crystalline powder. Its primary and well-established application is as a therapeutic agent (API) for the treatment of acute pancreatitis and disseminated intravascular coagulation (DIC). It functions by inhibiting proteolytic enzymes such as trypsin, kallikrein, plasmin, and thrombin, thereby reducing inflammation and abnormal coagulation. It is administered via intravenous infusion. As an active pharmaceutical ingredient, it is also relevant in pharmaceutical analysis as a reference standard or impurity standard for quality control during manufacturing and regulatory processes.

Physical Properties

Boiling Point: 508.6 °C at 760 mmHg

Flash Point: 261.4 °C

Analytical Data

Appearance: white crystal