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    5632-13-3

    Catalog No. EBD19665

    CAS 5632-13-3

    Name 4-Aminomethylquinoline

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    Basic Information

    Synonyms: 4-quinolylmethanamine

    Molecular Formula: C10H10N2

    Molecular Weight: 158.2

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    4-(Aminomethyl)quinoline is an organic compound featuring a quinoline ring system substituted with an aminomethyl group at the 4-position. This structure combines the aromatic heterocyclic scaffold of quinoline with a primary amine functional group, making it a versatile building block. Its primary application is as a pharmaceutical intermediate. The quinoline core is a privileged structure in medicinal chemistry, found in numerous drugs with diverse biological activities, including antimalarial, antibacterial, and anticancer agents. The reactive aminomethyl group serves as a key handle for further chemical modifications, allowing for the synthesis of more complex molecules, such as amides, ureas, or heterocyclic-fused systems, during drug discovery and development processes. Due to its bifunctional nature (aromatic heterocycle and primary amine), it is also utilized as a specialized organic synthesis building block in academic and industrial research for constructing nitrogen-containing heterocyclic libraries and functional materials.
    Physical Properties

    Boiling Point: 319.958 °C at 760 mmHg

    Flash Point: 173.268 °C

    Density: 1.157 g/cm3

    mg g kg ml l t