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    5604-46-6

    Catalog No. EBD18781

    CAS 5604-46-6

    Name 2-Amino-4,6-dichloropyrimidine-5-carbaldehyde

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    Basic Information

    Synonyms: 2-Amino-4,6-dichloropyrimidine-5-carbaldehyde 2-Amino-4,6-dichloropyrimidine-5-carboxaldehyde 2-Amino-4,6-dichloro-5-formylpyrimidine 2-amino-4,6-dichloro-5-pyrimidinecarbaldehyde

    Molecular Formula: C5H3Cl2N3O

    Molecular Weight: 192.0

    MDL Number: MFCD03001242

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    2-Amino-4,6-dichloropyrimidine-5-carbaldehyde is a heterocyclic organic compound featuring a pyrimidine core substituted with an amino group, two chlorine atoms, and a formyl group. This specific substitution pattern makes it a versatile and valuable building block in synthetic chemistry. Its primary and most significant application is as a key intermediate in the synthesis of pharmaceutical compounds. It serves as a crucial precursor in the production of various drugs, including antiviral agents and kinase inhibitors. The reactive aldehyde and chlorinated pyrimidine moieties allow for further functionalization and cyclization reactions to construct more complex molecular architectures found in active pharmaceutical ingredients (APIs). While its dominant use is in pharmaceutical synthesis, its well-defined structure also qualifies it as a specialized organic synthesis building block, particularly for constructing fused heterocyclic systems. It is commercially available for research and development purposes in medicinal chemistry.
    Physical Properties

    Melting Point: 208-224 °C

    Boiling Point: 411.6 °C at 760 mmHg

    Flash Point: 202.7 °C

    Density: 1.688 g/cm3

    Storage: 2-8°C

    Analytical Data

    Appearance: yellow solid

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