Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    56026-36-9

    Catalog No. EBD50844

    CAS 56026-36-9

    Name 6-Hydroxymethylnicotinic acid methyl ester

    Get Quote
    Basic Information

    Synonyms: Methyl6-(hydroxymethyl)nicotinate 6-Hydroxymethyl-nicotinicacidmethylester methyl6-(hydroxymethyl)pyridine-3-carboxylate 6-Hydroxymethylnicotinicacidmethylester

    Molecular Formula: C8H9NO3

    Molecular Weight: 167.16

    MDL Number: MFCD00643821

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    6-Hydroxymethyl nicotinic acid methyl ester is an organic compound featuring a pyridine ring substituted with a hydroxymethyl group at the 6-position and a methoxycarbonyl group at the 3-position. It is a white to off-white crystalline powder. This compound is primarily utilized as a key pharmaceutical intermediate. Its most notable application is in the synthesis of Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor used for the treatment of type 2 diabetes. The hydroxymethyl and ester functional groups make it a versatile building block for constructing more complex molecules, particularly those containing the nicotinic acid (pyridine-3-carboxylic acid) scaffold. As a functionalized pyridine derivative, it serves as a valuable heterocyclic building block in medicinal chemistry research. Its dual functionality allows for further chemical modifications, making it useful for the development of various bioactive compounds beyond its primary role in antidiabetic drug synthesis.
    Physical Properties

    Boiling Point: 293.4°Cat760mmHg

    Flash Point: 131.3°C

    Density: 1.244g/cm3

    mg g kg ml l t