L-Glutamine, CAS No. 56-85-9

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56-85-9

Catalog No. EBD3728598

CAS 56-85-9

Name L-Glutamine

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Basic Information

Synonyms: L-2-Aminoglutaramicacid levoglutamide H-Gln-OH L-Glutamicacid5-amide alpha-glutamine L-(+)-glutamine (2S)-2-amino-4-carbamoylbutanoicacid (S)-(+)-glutamine 2,5-Diamino-5-oxopentanoicacid,(S)- 2-Aminoglutaramicacid,L- glutamine,L- glutaminicacid L-(+)-glutamicacid-5-amide L(+)-Glutamine L(+)-Glutamicacid-5-amide

Molecular Formula: C5H10N2O3

Molecular Weight: 146.14

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Medicinal Chemistry > Pharmaceutical Excipients > Other Pharmaceutical Excipients

Product Description:

L-Glutamine is a conditionally essential amino acid, classified as a non-polar, neutral α-amino acid. It is the most abundant free amino acid in human blood and muscle tissue. Structurally, it features a side chain containing an amide group, which is a key functional moiety. Its primary applications are in the fields of life science research and pharmaceutical manufacturing. In cell culture, it serves as a crucial nitrogen and carbon source, supporting the growth of mammalian cells, particularly in the production of biopharmaceuticals like monoclonal antibodies and vaccines. As a pharmaceutical ingredient, it is used in parenteral nutrition formulations and oral supplements to support gut health, immune function, and muscle recovery in clinical settings. It also finds use as an excipient in certain drug formulations. Beyond its direct biological roles, L-glutamine is a metabolic precursor for the synthesis of other amino acids, nucleotides, and the antioxidant glutathione. It is generally recognized as safe (GRAS) for use in dietary supplements and medical foods.

Physical Properties

Melting Point: 185 °C (dec.)(lit.)

Boiling Point: 445.6 °C at 760 mmHg

Flash Point: 185°C

Density: 1.321 g/cm3

Solubility: H2O: 25 mg/mL

Refractivity: 6.8 ° (C=4, H2O)

Storage: −20°C

Analytical Data

Appearance: White crystalline powder