![N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide,CAS No. 557795-19-4.](https://public.whmall.com/system/0/chemical/image/2007/09/04/1188888888-52154_C22H27FN4O2.png "N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide,CAS No. 557795-19-4.")
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide CAS No.557795-19-4 / Cat No.EBD52154
舒尼替尼
舒尼替尼及其中间体(研发)
苏尼替尼
舒马替尼
舒林替尼碱
舒尼替尼碱
舒尼替尼
(Z)-N-(2-(二乙基氨基)乙基)-5-((5-氟-2-氧代吲哚啉-3-亚甲基)甲基)-2,4-二甲基-1H-吡咯-3-羧酰胺
(Z)-N-[2-(二乙氨基)乙基]-5-[(2-氧代-5-氟-3-吲哚啉亚基)甲基]-2,4-二甲基吡咯-3-甲酰胺
Properties
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Appearance:
yellow solid
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Density:
1.23 g/cm3
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Melting point:
189-191°C
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Boiling point:
572.136 °C at 760 mmHg
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Flashing point:
299.818 °C
NMR Spectrum
Prediction： H-NMR (DMSO-d6): 0.97 (t, 6H, J=7.08Hz, 2 x -CH2-CH3), 2.42 (s, 3H, -CH3), 2.44 (s, 3H, -CH3), 2.47-2.56 (m, 6H, 3 x -CH2-), 3.25-3.31 (m, 2H, -CO-NH-CH2-), 6.83-6.87 (m, IH, vinyl proton), 6.90-6.94 (t, IH, J=5.9Hz, aromatic ortho position), 7.43-7.47 (t, IH, J=5.6Hz, aromatic meta position), 7.74-7.78 (dd, IH, J=5.9Hz, aromatic ortho position), 7.72 (s, IH, aliphatic amide -NH-, D20 exchangeable), 10.90 (s, IH, pyrrole -NH-, D20 exchangeable), 13.68 (s, IH, indole -NH-, D20 exchangeable).
1H NMR
13C NMR
