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    55289-36-6

    Catalog No. EBD24106

    CAS 55289-36-6

    Name 3-bromo-2-methylaniline

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    Basic Information

    Synonyms: 3-Bromo-o-toluidine 2-Amino-6-bromotoluene 2-Bromo-6-aminotoluene

    Molecular Formula: C7H8BrN

    Molecular Weight: 186.05

    MDL Number: MFCD00051579

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    3-Bromo-2-methylaniline is an aromatic organic compound featuring a bromine atom at the 3-position and a methyl group at the 2-position on an aniline ring. It has a molecular formula of C7H8BrN and a molecular weight of 186.05 g/mol. This compound serves as a versatile building block in organic synthesis, particularly as a halogenated aniline derivative. Its primary application is as a synthetic intermediate in the pharmaceutical industry, where it is used to construct small-molecule drug candidates, especially those targeting kinase inhibitors or other bioactive heterocycles. The bromine atom enables cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), while the aniline group allows for further functionalization. Additionally, it is employed in the synthesis of agrochemicals and specialty chemicals. Due to its reactivity and structural features, it is also a common reagent in medicinal chemistry for fragment-based drug discovery. Proper handling is required as it may cause skin and eye irritation.
    Physical Properties

    Boiling Point: 248 °C(lit.)

    Flash Point: 110 °C

    Density: 1.51 g/mL at 25 °C(lit.)

    Refractivity: n20/D 1.619(lit.)

    Analytical Data

    Appearance: colorless to yellow liquid

    mg g kg ml l t