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    552-89-6

    Catalog No. EBD48551

    CAS 552-89-6

    Name 2-Nitrobenzaldehyde

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    Basic Information

    Synonyms: 2-Nitobenzaldehyde 2-Nitrobenzaldehyd o-nitrobenzaldehyde orthonitrobenzaldehyde o-Nitrobenzyldehyde 2-Nitrobenzaldehyde

    Molecular Formula: C7H5NO3

    Molecular Weight: 151.12

    MDL Number: MFCD00007132

    Categories: Synthetic Chemistry > Organic Building Blocks > Amines Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones

    Product Description:
    2-Nitrobenzaldehyde is an aromatic aldehyde featuring a nitro group at the ortho position relative to the aldehyde moiety. This yellow crystalline solid serves as a versatile synthetic building block in organic chemistry, primarily utilized for the construction of heterocyclic compounds such as indoles, quinolines, and benzodiazepines via condensation and reduction reactions. In pharmaceutical research, it is a key intermediate for the synthesis of small-molecule drug fragments, including precursors to antihypertensive agents (e.g., nifedipine analogs) and photolabile protecting groups (e.g., o-nitrobenzyl derivatives) used in caged compounds for biological studies. Its photoreactivity under UV light also makes it valuable in materials science for photo-patterning applications. The compound is stable under normal conditions but should be handled with care due to its irritant properties. It is widely available as a fine chemical for laboratory-scale synthesis and process development.
    Physical Properties

    Melting Point: 42-44 °C(lit.)

    Boiling Point: 153 °C/23 mmHg(lit.)

    Flash Point: 113 °C

    Density: 1,284 g/cm3

    Storage: Store at RT.

    Analytical Data

    Appearance: Yellow crystalline powder or needles

    mg g kg ml l t