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    5513-40-6

    Catalog No. EBD214201

    CAS 5513-40-6

    Name Cbz-L-Tyrosine benzyl ester

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    Basic Information

    Synonyms: L-Tyrosine,N-[(phenylmethoxy)carbonyl]-,phenylmethylester Tyrosine,N-carboxy-,dibenzylester Tyrosine,N-carboxy-,dibenzylester,L- N-(Benzyloxycarbonyl)tyrosinebenzylester N-Carboxy-L-tyrosinedibenzylester CBZ-L-TYROSINEBENZYLESTER Z-TYR-OBZL

    Molecular Formula: C24H23NO5

    Molecular Weight: 405.44

    MDL Number: MFCD00136670

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

    Product Description:
    N-(Benzyloxycarbonyl)-L-tyrosine benzyl ester is a protected derivative of the amino acid L-tyrosine. It features two benzyl protecting groups: one on the α-amino group (as a Cbz, or Z, group) and one on the carboxylic acid (as a benzyl ester). This dual protection renders the molecule stable and suitable for use in peptide synthesis, particularly in the classical solution-phase method. This compound serves as a crucial building block in the synthesis of peptides and peptide-like molecules. The Cbz group on the amine is stable under the conditions used for coupling but can be selectively removed via catalytic hydrogenation, allowing for the sequential elongation of peptide chains. Its primary application is in pharmaceutical research and development for constructing peptides containing tyrosine residues, which are important for biological activity in many therapeutic agents. As a specialty, protected amino acid derivative, it is not considered a generic organic synthesis reagent. Its use is predominantly confined to the field of peptide chemistry and the preparation of complex biomolecules for medicinal chemistry and life sciences applications.
    Physical Properties
    mg g kg ml l t