(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride, CAS No. 5505-63-5

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5505-63-5

Catalog No. EBD2198035

CAS 5505-63-5

Name (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride

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Basic Information

Synonyms: D-mannosaminehydrochloride D-Mannosamine,Hydrochloride D-Mannosamine,HCl 2-Amino-2-deoxy-D-mannopyranosehydrochloride (3R,4S,5R)-3,4,5,6-tetrahydroxy-L-norleucinehydrochloride(1:1) 2-amino-2-deoxy-D-mannosehydrochloride D-mannosamineHCl (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanalhydrochloride D-Mannosamine HCl

Molecular Formula: C6H14ClNO5

Molecular Weight: 215.63

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates

Product Description:

D-Mannosamine hydrochloride is a hydrochloride salt of an amino sugar, specifically the amino derivative of D-mannose. Its chemical name is (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride. This compound is a white to off-white crystalline powder that is soluble in water. This amino sugar is a crucial biochemical building block and a key intermediate in the biosynthesis of sialic acids, such as N-acetylneuraminic acid (Neu5Ac). Its primary applications are in life science research and pharmaceutical development. It serves as a precursor for the synthesis of sialic acid analogs, glycoconjugates, and glycomimetics, which are essential for studying cell-cell recognition, immune response, and pathogen-host interactions. It is also used in the development of carbohydrate-based vaccines and therapeutics. As a specialized biochemical reagent, it is not a general-purpose organic synthesis building block. Its value lies in its specific stereochemistry and role in glycobiology.

Physical Properties

Melting Point: 168 °C (dec.)(lit.)

Boiling Point: 532.5 °C at 760 mmHg

Flash Point: 275.8 °C

Solubility: H2O: 0.1 g/mL, clear, colorless

Storage: 2-8°C

Analytical Data

Appearance: White crystalline solid