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    550378-07-9

    Catalog No. EBD18914

    CAS 550378-07-9

    Name (R)-2-(Aminoethyl)-1-N-Boc-pyrrolidine

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    Basic Information

    Synonyms: tert-butyl(2R)-2-(2-aminoethyl)pyrrolidine-1-carboxylate 1-Pyrrolidinecarboxylicacid,2-(2-aminoethyl)-,1,1-dimethylethylester,(2R)- (R)-2-(Aminoethyl)-1-N-Boc-pyrrolidine

    Molecular Formula: C11H22N2O2

    Molecular Weight: 214.3

    MDL Number: MFCD04115290

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    The compound with CAS number 550378-07-9 is known as (R)-1-Boc-2-(2-aminoethyl)pyrrolidine. It is a chiral pyrrolidine derivative featuring a Boc-protected secondary amine on the pyrrolidine ring and a primary aminoethyl side chain. This structure makes it a versatile, bifunctional building block. Its primary application is in pharmaceutical research and development as a key chiral intermediate. The pyrrolidine scaffold is a privileged structure in medicinal chemistry, and the presence of two distinct, protected amine functionalities allows for selective derivatization. This compound is specifically used in the synthesis of bioactive molecules, including potential drug candidates targeting various diseases. As a chiral amine synthon, it is also employed in organic synthesis for constructing complex molecules. The Boc protecting group offers orthogonal deprotection strategies, facilitating its use in multi-step synthetic sequences.
    Physical Properties

    Boiling Point: 297.5 °C at 760 mmHg

    Flash Point: 133.7 °C

    Density: 1.029 g/cm3

    mg g kg ml l t