2-Benzoyl-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one, CAS No. 54761-87-4

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

54761-87-4

Catalog No. EBD32222

CAS 54761-87-4

Name 2-Benzoyl-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one

Get Quote

Basic Information

Synonyms: 2-(phenylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one 2-Benzoyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one 4H-Pyrazino[2,1-a]isoquinolin-4-one,2-benzoyl-1,2,3,6,7,11b-hexahydro- 2-Benzyl-1,2,3,6,7,11B-Hexahydro-4H-Pyrazion[2,1-A]Isoquinoline-4-One 2-Benzoyl-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one

Molecular Formula: C19H18N2O2

Molecular Weight: 306.36

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > APIs and Their Salts > Antiparasitics

Product Description:

The compound with CAS number 54761-87-4 is a key intermediate in the synthesis of Praziquantel. Its chemical structure is based on a tetrahydroisoquinoline core, which is a crucial heterocyclic scaffold for constructing the final active pharmaceutical ingredient (API). Praziquantel is a broad-spectrum anthelmintic drug and is the treatment of choice for schistosomiasis (bilharzia) and other trematode infections. As a critical synthetic precursor, this intermediate is produced on an industrial scale and is essential for the manufacturing process of the final API. Its primary and definitive application is within the pharmaceutical industry for producing antiparasitic medications. The synthesis and quality control of this intermediate are of high importance to ensure the efficacy and safety of the final drug product. Its production is a significant step in the global supply chain for essential medicines used in public health programs targeting parasitic diseases.

Physical Properties

Boiling Point: 539.904 °C at 760 mmHg

Flash Point: 256.971 °C

Density: 1.308 g/cm3