3,4-Bis(benzyloxy)benzaldehyde, CAS No. 5447-02-9

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5447-02-9

Catalog No. EBD16559

CAS 5447-02-9

Name 3,4-Bis(benzyloxy)benzaldehyde

Purity ≥98%

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Basic Information

Synonyms: 3,4-dibenzyloxybenzaldehyde 3,4-bis(benzyloxy)benzaldehyde 3,4-diphenoxybenzaldehyde

Molecular Formula: C21H18O3

Molecular Weight: 318.37

MDL Number: MFCD00004776

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Small Molecule Drug Fragments Medicinal Chemistry > Biochemicals and Life Science Reagents > Phytochemicals and Natural Products

Product Description:

3,4-Bis(benzyloxy)benzaldehyde is a benzaldehyde derivative featuring two benzyloxy protecting groups at the 3 and 4 positions of the aromatic ring. Its molecular formula is C21H18O3, and it serves as a key synthetic intermediate in organic chemistry, particularly for constructing complex molecules with a 3,4-dihydroxybenzaldehyde (protocatechualdehyde) core after deprotection. This compound is primarily utilized as a building block in the synthesis of pharmaceutical intermediates, including precursors for neuroprotective agents, anti-inflammatory drugs, and natural product analogs. It is also employed in the preparation of polyphenolic compounds and ligands for biological studies, where the benzyloxy groups provide stability during multi-step syntheses and are removable under mild hydrogenolysis conditions. Additionally, it finds application in the development of plant-derived bioactive molecules and synthetic analogs for medicinal chemistry research.

Physical Properties

Melting Point: 91-94 °C (dec.)(lit.)

Boiling Point: 492.4 °C at 760 mmHg

Flash Point: 243.9 °C

Density: 1.176 g/cm3

Analytical Data

Appearance: off-white solid

Purity: ≥98%