R-tetrahydropapaverine HCl, CAS No. 54417-53-7

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54417-53-7

Catalog No. EBD6278

CAS 54417-53-7

Name R-tetrahydropapaverine HCl

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Basic Information

Synonyms: (R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinolinehydrochloride R-(+)-TETRAHYDROPAPAVERINHYDROCHLORIDE (r)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline (R)-1-(3,4-DIMETHOXY-BENZYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINEHYDROCHLORIDE R-tetrahydropapaverineHCl R-(+)-Tetrahydropapaverin (R)-1-(3,4-DIMETHOXY-BENZYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINEHYDROCHLORID R-Tetrahydropapaverine R-BINAP20060917 (R)-tetrahydropapaverinehydrochloride (1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline R-Tetrahydropapaverinehydrochloride R-TATRAHYDROPAPAVERINEHCL (R)-tetrahydropapaverine

Molecular Formula: C20H25NO4

Molecular Weight: 343.42

MDL Number: MFCD09750421

Categories: Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

Product Description:

(R)-Tetrahydropapaverine hydrochloride is a chiral organic compound, specifically the hydrochloride salt of the (R)-enantiomer of tetrahydropapaverine. It is a derivative of the natural alkaloid papaverine, featuring a tetrahydroisoquinoline core structure. This compound is a key intermediate in the synthesis of more complex pharmaceutical agents. Its primary application is in medicinal chemistry research and development, particularly as a chiral building block for the synthesis of potential therapeutic agents targeting the central nervous system. (R)-Tetrahydropapaverine and its derivatives have been investigated for their biological activities, including interactions with adrenergic and dopaminergic receptors. It serves as a crucial precursor in the synthesis of novel compounds with potential applications as neuroprotective agents or for the treatment of neurological disorders. As a pharmaceutical intermediate, it is handled under controlled conditions in research and development laboratories. Its chiral nature makes it valuable for producing enantiomerically pure drug candidates, highlighting its role in modern asymmetric synthesis for drug discovery.

Physical Properties

Boiling Point: 475.8 °C at 760 mmHg

Flash Point: 202.7 °C