Ethyl 2-(pyridin-4-yl)acetate, CAS No. 54401-85-3

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

54401-85-3

Catalog No. EBD2050068

CAS 54401-85-3

Name Ethyl 2-(pyridin-4-yl)acetate

Get Quote

Basic Information

Synonyms: 4-Pyridylaceticacidethylester ethylpyridin-4-ylacetate Ethylpyridine-4-acetate Ethyl4-pyridylacetate ethyl4-pyridineacetate 4-pyridineaceticacidethylester Ethyl2-(pyridin-4-yl)acetate

Molecular Formula: C9H11NO2

Molecular Weight: 165.19

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

Ethyl 4-pyridylacetate is an organic compound featuring a pyridine ring substituted with an ethyl acetate group. It serves as a versatile synthetic building block, particularly valued for its pyridine moiety and activated methylene group, which can undergo various transformations such as hydrolysis, condensation, and alkylation reactions. Its primary application is in pharmaceutical research and development as a key intermediate. It is notably used in the synthesis of biologically active molecules, including potential drug candidates. For instance, it has been employed in routes to prepare compounds with anti-inflammatory or other therapeutic properties, leveraging the pyridine ring as a common pharmacophore in medicinal chemistry. As a liquid, it requires careful handling under standard laboratory conditions. It is typically used in organic synthesis and process chemistry for constructing more complex heterocyclic systems.

Physical Properties

Melting Point: 18-19 °C(lit.)

Boiling Point: 127-128 °C/14 mmHg(lit.)

Flash Point: 113 °C

Density: 1.079 g/mL at 25 °C(lit.)

Refractivity: n20/D 1.499(lit.)