3 - Ethynylaniline, CAS No. 54060-30-9

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

54060-30-9

Catalog No. EBD36514

CAS 54060-30-9

Name 3 - Ethynylaniline

Get Quote

Basic Information

Synonyms: 3-Ethynyl-phenylamine 3-ethynylphenylamine benzenamine,3-ethynyl- 3-Ethynylaniline m-aminophenylacetylene 3-aminophenylacetylene 3-ethynylbenzeneamine 3-ethynyl-benzenamin 3-ethynyl-Benzenamine Aminophenylacetylene,3- m-ethynylaniline

Molecular Formula: C8H7N

Molecular Weight: 117.15

MDL Number: MFCD00014779

Categories: Synthetic Chemistry > Organic Building Blocks > Amines Synthetic Chemistry > Organic Building Blocks > C-C Double and Triple Bonds

Product Description:

3-Ethynylaniline is an organic compound featuring both a primary aromatic amine group and a terminal alkyne (ethynyl) group at the meta position of the benzene ring. This dual functionality makes it a highly versatile building block in organic synthesis. The amine group allows for further derivatization via acylation, alkylation, or diazotization, while the terminal alkyne is a key handle for Sonogashira coupling, click chemistry (CuAAC), and other alkyne-based transformations. As a small molecule fragment, 3-ethynylaniline is widely employed in the pharmaceutical industry for constructing bioactive molecules, including kinase inhibitors, receptor modulators, and other drug candidates. Its rigid, planar structure and ability to participate in hydrogen bonding and ж╨-ж╨ interactions make it valuable in medicinal chemistry for optimizing target binding and pharmacokinetic properties. In materials science, this compound serves as a precursor for conjugated polymers, fluorescent probes, and surface-functionalized materials. It is typically handled as a solid or liquid under inert atmosphere due to the reactivity of the alkyne group. Standard safety precautions should be observed as it may cause skin and eye irritation.

Physical Properties

Melting Point: 27°C

Boiling Point: 92-93 °C (2 mmHg)

Flash Point: 59 °C

Density: 1.04

Refractivity: 1.614-1.616

Storage: 2-8°C

Safety Information

Packing Level: III

Hazard Category: 3

Transport Codes: 1993C

Analytical Data

Appearance: clear yellowish to brown liquid