(R)-(-)-1-(9-Anthryl)-2,2,2-trifluoroethanol is a chiral fluorinated alcohol derivative featuring an anthracene moiety. It is a white to off-white crystalline solid with a molecular formula of C₁₆H₁₁F₃O. The compound is characterized by its high optical purity and is commonly used as a chiral derivatizing agent or a chiral solvating agent (CSA) in nuclear magnetic resonance (NMR) spectroscopy for the determination of enantiomeric excess (ee) of other chiral compounds, particularly amines, alcohols, and carboxylic acids. Its primary application lies in the field of analytical chemistry and asymmetric synthesis. The anthracene group provides a strong shielding effect, while the trifluoromethyl group enhances the chemical shift differences (Δδ) between the diastereotopic signals of the analyte complex, enabling accurate ee measurement. Beyond analytical use, it serves as a precursor or chiral auxiliary in the synthesis of more complex chiral ligands and catalysts used in enantioselective transformations. The compound is sensitive to air and moisture and should be stored under an inert atmosphere. It is a valuable tool for researchers in organic chemistry and pharmaceutical development for rapid chiral analysis, supporting the development of enantiomerically pure drugs and fine chemicals.