D-Leucinol, CAS No. 53448-09-2

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53448-09-2

Catalog No. EBD38171

CAS 53448-09-2

Name D-Leucinol

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Basic Information

Synonyms: 1-Pentanol,2-amino-4-methyl-,(2R)- (2R)-1-hydroxy-4-methylpentan-2-aminium D(-)-Leucinol (2R)-2-Amino-4-methylpentan-1-ol (R)-2-Amino-3-methyl-1-butanol D-Leucinol d-eucinol h-d-leu-ol (r)-leucinol h-d-leucinol (r)-(-)-leucinol d(-)-leucinolee

Molecular Formula: C6H15NO

Molecular Weight: 117.19

MDL Number: MFCD00004734

Categories: Synthetic Chemistry > Organic Building Blocks > Amines Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

D-Leucinol is a chiral amino alcohol derived from D-leucine, featuring a primary amine and a hydroxyl group on a branched alkyl chain. It serves as a key chiral building block in asymmetric synthesis, particularly for the preparation of chiral ligands, auxiliaries, and catalysts. In pharmaceutical chemistry, it is utilized as an intermediate in the synthesis of bioactive molecules, including enzyme inhibitors and receptor modulators, due to its ability to introduce stereochemical control. Additionally, its dual functional groups enable applications in peptide chemistry and the production of specialty chemicals.

Physical Properties

Boiling Point: 198-200 °C/768 mmHg(lit.)

Flash Point: 90 °C

Density: 0.917 g/mL at 25 °C(lit.)

Refractivity: n20/D 1.4496(lit.)

Storage: 0-6°C

Safety Information

Packing Level: III

Hazard Category: /

Transport Codes: 1993

Analytical Data

Appearance: clear pale yellow viscous liquid