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    527-72-0

    Catalog No. EBD47875

    CAS 527-72-0

    Name thiophene-2-carboxylic acid

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    Basic Information

    Synonyms: 2-Thiophenecarboxylicacid 2-Thenoicacid 2-ThiophenecaroxylicAcid thiophene-2-carboxylate LABOTEST-BBLT02016392 AKOSB022791 α-thiophenecarboxylicacid

    Molecular Formula: C5H4O2S

    Molecular Weight: 128.15

    MDL Number: MFCD00005437

    Categories: Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters Materials Chemistry > Optoelectronic and Organic Semiconductor Materials > Thiophene, Pyrene, and Fluorene Derivatives

    Product Description:
    Thiophene-2-carboxylic acid is a heterocyclic compound featuring a thiophene ring substituted with a carboxylic acid group at the 2-position. It has a molecular formula of C5H4O2S and a molecular weight of 128.15 g/mol. This compound serves as a fundamental building block in organic synthesis, particularly for constructing thiophene-containing molecules. Its primary application lies in the pharmaceutical industry as a key intermediate for synthesizing various bioactive molecules, including antibiotics (e.g., cephalosporins), anti-inflammatory agents, and other therapeutic compounds. The carboxylic acid group allows for further derivatization through esterification, amidation, or coupling reactions. Additionally, thiophene-2-carboxylic acid is utilized in agrochemical synthesis and materials science for producing conductive polymers and organic semiconductors. It is a stable, crystalline solid with a melting point of 128-130буC and is typically stored under ambient conditions.
    Physical Properties

    Melting Point: 125-127 °C(lit.)

    Boiling Point: 260 °C(lit.)

    Flash Point: 259-261°C

    Density: 1.42

    Solubility: water: 80 g/L (20 °C)

    Analytical Data

    Appearance: white to light yellow crystal powder

    mg g kg ml l t