MeOQ, CAS No. 5263-87-6

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5263-87-6

Catalog No. EBD2204519

CAS 5263-87-6

Name MeOQ

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Basic Information

Synonyms: MeOQ 6-Methoxyquinoline Methoxyquinoline,95%

Molecular Formula: C10H9NO

Molecular Weight: 159.18

MDL Number: MFCD00006800

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

6-Methoxyquinoline is a heterocyclic aromatic compound featuring a quinoline core substituted with a methoxy group at the 6-position. It is a versatile organic building block with significant utility in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmacologically active compounds. Notably, it serves as a crucial precursor in the production of antimalarial drugs, such as primaquine and tafenoquine. The quinoline scaffold is also explored in the development of other therapeutic agents, including anticancer and antimicrobial drugs, due to its ability to interact with biological targets. Beyond its role as a pharmaceutical intermediate, 6-methoxyquinoline is a valuable synthon in organic synthesis for constructing more complex heterocyclic systems. It is typically handled as a solid or liquid and requires standard precautions for handling organic bases.

Physical Properties

Melting Point: 18-20 °C(lit.)

Boiling Point: 140-146 °C/15 mmHg(lit.)

Flash Point: 113 °C

Density: 1.15 g/mL at 20 °C(lit.)

Solubility: insoluble

Refractivity: n20/D 1.625(lit.)

Storage: 2-8°C

Analytical Data

Appearance: colorless to light yellow liquid