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    52605-49-9

    Catalog No. EBD40494

    CAS 52605-49-9

    Name Ethyl sarcosinate hydrochloride

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    Basic Information

    Synonyms: Ethylsarcosinatehydrochloride H-Sar-OEt.HCl ethylN-methylglycinate ethylN-methylglycinatehydrochloride(1:1) H-Sar-OEt·HCl

    Molecular Formula: C5H12ClNO2

    Molecular Weight: 153.61

    MDL Number: MFCD00012506

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    Sarcosine ethyl ester hydrochloride is an organic salt derived from the amino acid sarcosine (N-methylglycine). It is a white to off-white crystalline powder with the molecular formula C5H12ClNO2. This compound serves as a versatile building block in organic synthesis, particularly valued for its bifunctional nature containing both an ester group and a secondary amine moiety. Its primary and most significant application is in the pharmaceutical industry as a key intermediate. It is notably used in the synthesis of various active pharmaceutical ingredients (APIs), including certain ACE inhibitors for cardiovascular diseases and other therapeutic agents. The molecule acts as a precursor for introducing the N-methylglycine ethyl ester fragment into more complex molecular architectures. Beyond its role as a pharmaceutical intermediate, sarcosine ethyl ester hydrochloride is also employed in peptide synthesis and as a starting material for the preparation of surfactants and corrosion inhibitors. It should be handled with standard laboratory precautions, avoiding inhalation and contact with skin and eyes.
    Physical Properties

    Melting Point: ~125 °C

    Boiling Point: 138.6 °C at 760 mmHg

    Flash Point: 37.6 °C

    Solubility: H2O: 0.1 g/mL, clear

    Analytical Data

    Appearance: white to off-white crystalline solid

    mg g kg ml l t