1-Cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride, CAS No. 52-49-3

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

52-49-3

Catalog No. EBD2212376

CAS 52-49-3

Name 1-Cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride

Get Quote

Basic Information

Synonyms: 1-Cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-olhydrochloride benzhexolhydrochloride 1-cyclohexyl-1-phenyl-3-(1-piperidyl)propan-1-olhydrochloride alpha-Cyclohexyl-alpha-phenyl-1-piperidinepropanol,HCl Trihexane Trihexy Trihexyphenidylhydrochloride 1-Cyclohexyl-1-Phenyl-3-PiperidinePropanolHydrochloride TrihexyphenidylHCL 1-cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-olhydrochloride(1:1)

Molecular Formula: C20H32ClNO

Molecular Weight: 337.93

MDL Number: MFCD00058212

Categories: Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

Product Description:

Trihexyphenidyl hydrochloride is a synthetic anticholinergic agent, chemically known as α-cyclohexyl-α-phenyl-1-piperidinepropanol hydrochloride. It is a white, crystalline powder that is freely soluble in water and alcohol. This compound is primarily used as an active pharmaceutical ingredient (API) for the treatment of Parkinson's disease and drug-induced extrapyramidal symptoms. It functions as a competitive antagonist at muscarinic acetylcholine receptors (M1), helping to restore the balance between acetylcholine and dopamine in the basal ganglia, thereby alleviating tremors, rigidity, and other motor symptoms associated with parkinsonism. Trihexyphenidyl hydrochloride is typically administered orally in tablet form. Common side effects are related to its anticholinergic properties and may include dry mouth, blurred vision, constipation, and urinary retention. It is listed in various pharmacopoeias, including the USP and BP, and is considered a first-generation antiparkinsonian drug.

Physical Properties

Boiling Point: 447.9 °C at 760 mmHg

Flash Point: 211 °C

Solubility: H2O: soluble