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    519188-72-8

    Catalog No. EBD3731515

    CAS 519188-72-8

    Name (3R,4R)-rel-3,4-Pyrrolidinediol, hydrochloride (1:1)

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    Basic Information

    Synonyms: 反式-3,4-二羟基吡咯烷盐酸盐 反式-3,4-二羟基吡咯烷盐酸盐 反式-吡咯烷-3,4-二醇盐酸盐

    Molecular Formula: C4H10ClNO2

    Molecular Weight: 139.58

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    Trans-3,4-Dihydroxypyrrolidine hydrochloride is a heterocyclic amine derivative featuring a pyrrolidine ring substituted with two hydroxyl groups in a trans configuration. It is commonly supplied as a hydrochloride salt to enhance its stability and handling properties. This compound serves as a crucial chiral building block and intermediate in pharmaceutical synthesis. Its primary application is in the development of glycosidase inhibitors, a class of drugs with therapeutic potential for conditions such as diabetes, viral infections (e.g., influenza), and lysosomal storage disorders. The molecule's structure mimics monosaccharide moieties, allowing it to competitively inhibit enzymes that process carbohydrates. As a versatile synthon containing both amine and hydroxyl functionalities, it is also employed in organic and medicinal chemistry research for constructing more complex nitrogen-containing heterocycles and bioactive molecules. Its chirality makes it valuable for producing enantiomerically pure compounds.
    Physical Properties
    mg g kg ml l t