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    51239-46-4

    Catalog No. EBD2044772

    CAS 51239-46-4

    Name 4-(AMINOMETHYL)BENZENEBORONIC ACID

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    Basic Information

    Synonyms: 4-(aminomethyl)phenylboronic acid

    Molecular Formula: C7H10BNO2

    Molecular Weight: 150.97

    Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    4-(Aminomethyl)phenylboronic acid is an organic compound featuring both a primary amine (-CH2NH2) and a boronic acid (-B(OH)2) functional group attached to a benzene ring. This bifunctional structure makes it a versatile building block in synthetic chemistry. Its primary application is as a key intermediate in the synthesis of more complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions facilitated by the boronic acid group. The amine group serves as a handle for further derivatization, such as amide bond formation or as a coordination site. It is commonly used in the preparation of pharmaceutical intermediates, bioactive compounds, and functional materials where a phenylboronic acid moiety linked to an amine-containing side chain is required. The compound is typically handled under inert atmosphere due to the sensitivity of the boronic acid group to protodeboronation and oxidation. It is a solid at room temperature and requires storage in a cool, dry place.
    Physical Properties

    Boiling Point: 337.7 °C at 760 mmHg

    Flash Point: 158.1 °C

    Density: 1.18 g/cm3

    mg g kg ml l t