Levarterenol bitartrate, CAS No. 51-40-1

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51-40-1

Catalog No. EBD39213

CAS 51-40-1

Name Levarterenol bitartrate

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Basic Information

Synonyms: norepinephrinehydrogentartrate Norepinephrinebitartrate Norepinephrinebitartrateanhydrous (-)-Noradrenaline()-bitartrate (-)-Norepinephrinebitartrate (-)-R-Norepinephrinebitartrate Arterenolbitartrate L-Noradrenalinebitartrate Levarterenolbitartrate Levophed Levophedbitartrate NSC169106 Noradrenalinbitartrate Noradrenalinbitartrate,l- Noradrenalineacidtartrate Noradrenalinehydrogentartrate Noradrenalinetartrate Noradrenaline,tartrate(1:1) Norartrinalbitartrate Norepinephrinetartrate l-Arterenolbitartrate l-Arterenold-bitartrate l-Noradrenalined-bitartrate l-Noradrenalinetartrate l-Norepinephrinebitartrate 1,2-Benzenediol,4-((1R)-2-amino-1-hydroxyethyl)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1)(salt) 1,2-Benzenediol,4-(2-amino-1-hydroxyethyl)-,(R)-,(R-(R*,R*))-2,3-dihydroxybutanedioate(1:1) Benzylalcohol,alpha-(aminomethyl)-3,4-dihydroxy-,(-)-,tartrate(1:1) Benzylalcohol,alpha-(aminomethyl)-3,4-dihydroxy-,(-)-,tartrate(1:1)(salt) 4-(2-amin

Molecular Formula: C12H17NO9

Molecular Weight: 319.266

Categories: Medicinal Chemistry > APIs and Their Salts > Cardiovascular Drugs Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

Product Description:

Levarterenol bitartrate, also known as norepinephrine bitartrate, is the bitartrate salt form of norepinephrine. It is a direct-acting sympathomimetic amine that functions as a potent alpha-adrenergic and moderate beta-adrenergic receptor agonist. The compound is a white to off-white crystalline powder. Its primary and most critical application is as an active pharmaceutical ingredient (API) in emergency medicine. It is used intravenously to treat severe hypotension, acute hypotension, and cardiac arrest, particularly in critical care settings. It acts by increasing blood pressure and cardiac output through vasoconstriction and positive inotropic effects. Additionally, due to its role as a key neurotransmitter in the central nervous system, it is relevant in the context of drugs targeting neurological conditions related to catecholamine pathways. This substance is listed in major pharmacopoeias (e.g., USP, Ph. Eur.) and is strictly regulated for pharmaceutical use. It requires careful handling and administration due to its potent cardiovascular effects.

Physical Properties

Boiling Point: 442.6 °C at 760 mmHg

Flash Point: 221.5 °C