(S)-3-Acetoxy-4-(trimethylammonio)butanoate hydrochloride, CAS No. 5080-50-2

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5080-50-2

Catalog No. EBD7598

CAS 5080-50-2

Name (S)-3-Acetoxy-4-(trimethylammonio)butanoate hydrochloride

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Basic Information

Synonyms: (S)-3-Acetoxy-4-(trimethylammonio)butanoatehydrochloride O-Acetyl-L-carnitinehydrochloride (R)-3-Acetoxy-4-(trimethylammonio)butyratehydrochloride R(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminiumchloride Levacecarninehydrochloride AcetylL-carnitineHCL Acetyl-L-CarnitineHCL N-Acetyl-L-CarnitineHCL (2R)-2-(acetyloxy)-3-carboxy-N,N,N-trimethylpropan-1-aminiumchloride Acetyl-L-carnitineHydrochloride

Molecular Formula: C9H18ClNO4

Molecular Weight: 239.7

MDL Number: MFCD00082230

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Medicinal Chemistry > Pharmaceutical Excipients > Novel and Functional Excipients

Product Description:

O-Acetyl-L-carnitine hydrochloride (ALCAR) is the acetyl ester derivative of the amino acid L-carnitine. It is a white to off-white crystalline powder that is highly soluble in water. This compound is a naturally occurring substance in the body, primarily synthesized in the brain, liver, and kidneys. Its primary application is in the pharmaceutical and nutraceutical industries. ALCAR functions as a mitochondrial carrier, facilitating the transport of acetyl groups into the mitochondria for energy production. It is extensively researched and used as a dietary supplement and a potential therapeutic agent for supporting cognitive function, neuroprotection, and addressing conditions related to mitochondrial dysfunction and age-related cognitive decline. It is also investigated for its role in improving sperm motility and metabolic health. Due to its physiological role and safety profile, it is also considered a functional excipient in certain pharmaceutical formulations aimed at enhancing bioavailability or providing specific metabolic support.

Physical Properties

Color: white to off-white

Melting Point: 194 °C (dec.)(lit.)

Solubility: H2O: 100 mg/mL

Refractivity: -28 ° (C=1, H2O)

Storage: 2-8°C

Analytical Data

Appearance: Crystallline powder