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    50358-35-5

    Catalog No. EBD541180

    CAS 50358-35-5

    Name 5-amino-6-methylquinoline

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    Basic Information

    Synonyms: 6-methylquinolin-5-amine 5-Quinolinamine,6-methyl- 5-amino-6-methylquinoline 6-methyl-quinolin-5-ylamine 6-methyl-[5]quinolylamine 6-Methyl-[5]chinolylamin 6-Methyl-5-amino-chinolin

    Molecular Formula: C10H10N2

    Molecular Weight: 158.2

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    6-Methylquinolin-5-amine is an organic compound featuring a quinoline core substituted with a methyl group at the 6-position and an amino group at the 5-position. It serves as a versatile and important heterocyclic building block in organic synthesis, particularly in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmacologically active compounds. For instance, it is a crucial precursor in the development of kinase inhibitors, such as certain c-Met inhibitors, which are investigated for their potential in cancer therapy. The amino group provides a reactive site for further functionalization, enabling the construction of complex molecular architectures. This compound is typically handled as a solid and requires storage under inert conditions. It is used in research and development settings for the construction of novel drug candidates targeting a range of diseases, underscoring its value in the discovery of new therapeutic agents.
    Physical Properties

    Melting Point: 133-137 °C

    Boiling Point: 326.2 °C at 760 mmHg

    Flash Point: 177.2 °C

    Density: 1.169 g/cm3

    mg g kg ml l t