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    5004-07-9

    Catalog No. EBD2333254

    CAS 5004-07-9

    Name 4-(1-Pyrrolidinyl)piperidine

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    Basic Information

    Synonyms: 4-(pyrrolidin-1-yl)piperidine 4-(1-Pyrrolidinyl)piperidine

    Molecular Formula: C9H18N2

    Molecular Weight: 154.25

    MDL Number: MFCD00038011

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    4-(1-Pyrrolidinyl)piperidine is a bicyclic amine compound featuring a piperidine ring substituted at the 4-position with a pyrrolidine group. This structure makes it a versatile nitrogen-containing heterocyclic building block. This compound is primarily utilized as a key intermediate in pharmaceutical research and development. Its structural motif is found in the synthesis of various bioactive molecules, including potential drug candidates targeting the central nervous system and other therapeutic areas. The presence of both secondary and tertiary amine functionalities within a constrained ring system allows it to serve as a scaffold for constructing more complex pharmacophores. As a bifunctional amine, it also finds use in organic synthesis as a building block and as a ligand or base in certain catalytic reactions. Its dual-ring system contributes to specific steric and electronic properties that can be leveraged in medicinal chemistry.
    Physical Properties

    Melting Point: 53-56 °C(lit.)

    Boiling Point: 228.8 °C at 760 mmHg

    Flash Point: 92 °C

    Density: 0.989 g/cm3

    Analytical Data

    Appearance: white crystals

    mg g kg ml l t