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    4926-28-7

    Catalog No. EBD541048

    CAS 4926-28-7

    Name 2 Bromo-4-methyl pyridine

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    Basic Information

    Synonyms: 2-bromo-4-methylpyridine 2Bromo-4-methylpyridine 2-Bromo-4-picoline 4-methyl-2-bromopyridine

    Molecular Formula: C6H6BrN

    Molecular Weight: 172.02

    MDL Number: MFCD00082590

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    2-Bromo-4-methylpyridine is an organic compound featuring a pyridine ring substituted with a bromine atom at the 2-position and a methyl group at the 4-position. It is a halogenated heterocyclic building block, typically appearing as a colorless to pale yellow liquid or low-melting solid. This compound is primarily employed as a versatile synthetic intermediate in organic and medicinal chemistry. The bromine atom at the 2-position of the pyridine ring is highly reactive in cross-coupling reactions, such as Suzuki, Stille, and Negishi couplings, enabling the introduction of various aryl, heteroaryl, or alkyl groups. This makes it a valuable precursor for constructing more complex molecules, particularly in the synthesis of pharmaceuticals, agrochemicals, and functional materials. It is frequently used to prepare substituted pyridine derivatives that serve as key intermediates for active pharmaceutical ingredients (APIs) and other bioactive compounds. As a reactive halopyridine, it requires careful handling under inert atmosphere and should be stored away from light and moisture. Its primary value lies in its utility as a fundamental chemical building block for research and development across multiple chemical sectors.
    Physical Properties

    Boiling Point: 87 °C/10 mmHg(lit.)

    Flash Point: 113 °C

    Density: 1.545 g/mL at 25 °C(lit.)

    Refractivity: n20/D 1.561(lit.)

    Analytical Data

    Appearance: Colorless to orange oily liquid

    mg g kg ml l t