2,5-Dihydroxybenzoic acid, CAS No. 490-79-9

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490-79-9

Catalog No. EBD541055

CAS 490-79-9

Name 2,5-Dihydroxybenzoic acid

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Basic Information

Synonyms: Hydroquinonecarboxylicacid 2,5-Dhba 2,5-dihydroxy-benzoicaci 2,5-Dioxybenzoicacid 5-Hydroxysalicylicacid 5-hydroxy-salicylicaci acido2,5-diidrossibenzoico Benzoicacid,2,5-dihydroxy- 2,5-dihydroxybenzoicacid Gentisicacid DHB

Molecular Formula: C7H6O4

Molecular Weight: 154.12

MDL Number: MFCD00002460

Categories: Medicinal Chemistry > Pharmaceutical Excipients > Transdermal Penetration Enhancers

Product Description:

2,5-Dihydroxybenzoic acid, also known as gentisic acid, is a dihydroxybenzoic acid derivative featuring two hydroxyl groups at the 2 and 5 positions on the benzene ring. It is a metabolite of salicylic acid and possesses both antioxidant and anti-inflammatory properties. In biochemical research, it is widely used as a matrix for matrix-assisted laser desorption/ionization (MALDI) mass spectrometry, particularly for the analysis of peptides, proteins, and synthetic polymers. Additionally, it serves as a key building block in organic synthesis for the preparation of pharmaceuticals, dyes, and metal-organic frameworks (MOFs). Its ability to chelate metal ions also makes it relevant in coordination chemistry and as a potential therapeutic agent for inflammatory disorders.

Physical Properties

Melting Point: 203-207 °C

Boiling Point: 406.9 °C at 760 mmHg

Flash Point: 214 °C

Density: 1.559 g/cm3

Solubility: soluble in water

Analytical Data

Appearance: white to light beige crystalline powder