4-Bromomethyl-1,2-dihydroquinolin-2-one, CAS No. 4876-10-2

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4876-10-2

Catalog No. EBD4039

CAS 4876-10-2

Name 4-Bromomethyl-1,2-dihydroquinolin-2-one

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Basic Information

Synonyms: 4-(BROMOMETHYL)-2(1H)-QUINOLINONE 4-BROMOMETHYLQUINOLINONE 2(1H)-QUINOLINONE,4-(BROMOMETHYL)- 4-BromomethylCarbostyril 4-(bromomethyl)-2-hydroxyquinoline- 4-(bromomethyl)quinolin-2(1H)-one 4-Bromomethyl-1,2-dihydroquinolin-2-one 4-Bromomethyl-1,2-Dihydroquinoline-2-One 4-Bromomethyl-2-quinolinol

Molecular Formula: C10H8BrNO

Molecular Weight: 238.08

MDL Number: MFCD03426152

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

Product Description:

4-Bromomethylquinolin-2(1H)-one is a heterocyclic organic compound featuring a quinolin-2-one core substituted with a bromomethyl group at the 4-position. This structure combines a privileged heterocyclic scaffold with a reactive benzylic bromide functional group. Its primary application is as a versatile synthetic intermediate in medicinal chemistry. The bromomethyl group serves as a key reactive handle for further functionalization, particularly through nucleophilic substitution or cross-coupling reactions. This allows for the efficient construction of more complex molecules, especially those containing the quinolin-2-one pharmacophore, which is a common structural motif in bioactive compounds and drug candidates. Due to its dual role as a heterocyclic building block and an alkylating agent, it is valuable for the synthesis of libraries of compounds for biological screening and the development of potential therapeutic agents targeting various diseases.

Physical Properties

Melting Point: 255-258°C

Boiling Point: 391.8 °C at 760 mmHg

Flash Point: 190.8 °C

Density: 1.542 g/cm3

Analytical Data

Appearance: White-like powder