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    481048-22-0

    Catalog No. EBD2338343

    CAS 481048-22-0

    Name (R)-2-iodo-3-(iodomethyl)but-1-ene

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    Basic Information

    Molecular Formula: C5H8I2

    Molecular Weight: 321.93

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Special Functional Group Blocks

    Product Description:
    (R)-2-Iodo-3-(iodomethyl)but-1-ene is a chiral, diiodinated organic compound featuring a terminal alkene group. Its molecular structure contains two iodine atoms at distinct positions, making it a versatile and reactive synthetic building block. The presence of both a vinylic iodide and a benzylic-type iodide, along with the alkene functionality, allows for diverse chemical transformations. This compound is primarily utilized in advanced organic synthesis as a key chiral intermediate. Its main application lies in the construction of complex molecular architectures, particularly in medicinal chemistry research for the synthesis of potential drug candidates. The iodine atoms serve as excellent handles for cross-coupling reactions (e.g., Suzuki, Stille, Negishi), while the alkene can undergo further functionalization such as hydroboration or epoxidation. As a specialized, multi-functional halide, it is not a commodity chemical but a research-grade reagent. Its chiral nature ((R)-configuration) is crucial for introducing stereochemistry into target molecules. Handling requires standard precautions for iodinated compounds, including protection from light and moisture to prevent decomposition.
    Physical Properties
    mg g kg ml l t