2,3-trans-flavan-3,4-diol, CAS No. 480-17-1

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480-17-1

Catalog No. EBD487839

CAS 480-17-1

Name 2,3-trans-flavan-3,4-diol

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Basic Information

Synonyms: 2,3-trans-flavan-3,4-diol (+)-leucocyanidin leucocianidol Leucocianidol[INN:DCF] Leucocyanidin 2-(3,4-Dihydroxyphenyl)-3,4,5,7-chromantetrol Flavan-3,3',4,4',5,7-hexol Leucocianidolum Leucocianidolum[INN-Latin] UNII-RAP1D6110C VitaminPfaktor 2H-1-Benzopyran-3,4,5,7-tetrol,2-(3,4-dihydroxyphenyl)-3,4-dihydro 3,3',4,4',5,7-Flavanhexol 2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,4,5,7-tetrol (2R,3S,4S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,4,5,7-tetrol LeucocyanidinPolymer

Molecular Formula: C15H14O7

Molecular Weight: 306.27

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Phytochemicals and Natural Products Medicinal Chemistry > APIs and Their Salts > Other Drugs

Product Description:

2,3-trans-Flavan-3,4-diol, also known as leucocyanidin, is a type of flavan-3,4-diol, which belongs to the proanthocyanidin class of natural polyphenols. It is a colorless compound that serves as a key biosynthetic precursor to anthocyanin pigments and condensed tannins (proanthocyanidins) in plants. Its structure features a flavan skeleton with two hydroxyl groups at the 3 and 4 positions in a trans configuration. Leucocyanidin is primarily studied for its biological activities and potential therapeutic applications. It exhibits significant antioxidant properties, helping to neutralize free radicals. Research indicates it may possess anti-inflammatory, anti-diabetic, and cardioprotective effects. It is also investigated for its role in plant biochemistry and as a starting material for the synthesis of more complex flavonoids and proanthocyanidins in both natural product research and medicinal chemistry. As a natural product derivative, it is of interest in the development of nutraceuticals and phytopharmaceuticals. Its use is primarily confined to research settings for studying flavonoid metabolism, biosynthesis, and for evaluating biological activities relevant to human health.

Physical Properties

Boiling Point: 641.5 °C at 760 mmHg

Flash Point: 341.8 °C

Density: 1.709 g/cm3