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    478646-28-5

    Catalog No. EBD39742

    CAS 478646-28-5

    Name (R)-2-N-Cbz-aminopentane-1,5-diol

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    Basic Information

    Synonyms: benzyl[(1R)-4-hydroxy-1-(hydroxymethyl)butyl]carbamate (R)-2-N-Cbz-aminopentane-1,5-diol

    Molecular Formula: C13H19NO4

    Molecular Weight: 253.29

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-2-N-Cbz-aminopentane-1,5-diol is a chiral organic compound featuring a 1,5-diol backbone and a Cbz-protected primary amine group at the stereogenic center. The presence of the Cbz (carboxybenzyl) group serves as a standard protecting group for amines in peptide and organic synthesis, while the diol functionality offers additional sites for chemical modification. This compound is primarily utilized as a chiral building block or intermediate in pharmaceutical research and development. Its defined (R)-configuration makes it valuable for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) or complex molecules where stereochemistry is critical for biological activity. The molecule can be further elaborated through reactions at the amine (after deprotection) or the hydroxyl groups. As a bifunctional chiral synthon, it finds application in constructing more complex molecular architectures, particularly in medicinal chemistry for exploring structure-activity relationships. It is typically handled as a research chemical under standard laboratory safety protocols.
    Physical Properties

    Boiling Point: 485.2°C at 760 mmHg

    Flash Point: 247.2°C

    Density: 1.192g/cm3

    mg g kg ml l t