(3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine hydrochloride, CAS No. 477600-68-3

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477600-68-3

Catalog No. EBD3315348

CAS 477600-68-3

Name (3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine hydrochloride

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Basic Information

Synonyms: (3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine hydrochloride (3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine hydrochloride (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride (3R,4R)-cis-1-Benzyl-4-methyl-3-(methylamino)piperidine dihydrochloride cis-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-, hydrochloride (1:2), (3R,4R)-rel- 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-, dihydrochloride, (3R,4R)-rel- cis-1-Benzyl-N-methyl-4-methylpiperidin-3-amine dihydrochloride (3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine hydrochloride (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine hydrochloride

Molecular Formula: C14H23ClN2

Molecular Weight: 254.8

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

Product Description:

(3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine hydrochloride is a chiral piperidine derivative, specifically a cis-1-benzyl-3-(methylamino)-4-methylpiperidine dihydrochloride salt. It serves as a crucial synthetic intermediate in pharmaceutical research and development. This compound is primarily utilized in the synthesis of novel sigma-1 receptor ligands and modulators. Research indicates its application in developing potential therapeutic agents targeting the central nervous system (CNS), with investigations into its role for treating conditions such as neuropathic pain, depression, and neurodegenerative disorders. The chiral, substituted piperidine core is a privileged scaffold in medicinal chemistry for CNS-active compounds. As a high-purity building block, it is employed in structure-activity relationship (SAR) studies and the optimization of drug candidates. Handling requires standard laboratory safety precautions for amine hydrochlorides.

Physical Properties