(S)-(-)-1,1-Diphenyl-1,2-propanediol, CAS No. 46755-94-6

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46755-94-6

Catalog No. EBD433232

CAS 46755-94-6

Name (S)-(-)-1,1-Diphenyl-1,2-propanediol

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Basic Information

Synonyms: S(-)-1,1-diphenyl-1,2-propanediol (S)-(?-1,1-Diphenyl-1,2-propanediol (2S)-1,1-diphenylpropane-1,2-diol (S)-(-)-1,1-Diphenyl-1,2-propanediol (S)-(-)-1,1,-diphenyl-1,2-propanediol (S)-(-)-1,1-Diphenylpropane-1,2-diol S-(-)-1,1-diphenylpropane-1,2-diol (2S)-1,1-diphenyl-1,2-propanediol (S)-1.1-diphenyl-propanediol-(1.2)

Molecular Formula: C15H16O2

Molecular Weight: 228.29

MDL Number: MFCD00134287

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

S(-)-1,1-Diphenyl-1,2-propanediol is a chiral diol compound characterized by a central carbon bearing two phenyl groups and a hydroxymethyl substituent. Its specific S-configuration at the stereogenic center makes it a valuable non-racemic building block in asymmetric synthesis. This compound is primarily utilized as a chiral intermediate or ligand precursor in pharmaceutical research and development. Its structure, featuring two phenyl rings and a flexible side chain, is conducive to acting as a chiral auxiliary or as a component in the synthesis of more complex, biologically active molecules. The diol functionality allows for further chemical modifications, enabling its incorporation into target structures requiring specific stereochemistry. While its primary application domain is in medicinal chemistry as a chiral synthon, its well-defined structure and availability in enantiomerically pure form also position it as a specialized organic synthesis building block for academic and industrial research focused on stereoselective reactions.

Physical Properties

Melting Point: 89-92 °C(lit.)

Boiling Point: 406.6 °C at 760 mmHg

Flash Point: 195.7 °C

Density: 1.152 g/cm3