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    464-43-7

    Catalog No. EBD2199780

    CAS 464-43-7

    Name (1R,2S,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol

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    Basic Information

    Synonyms: (+)-borneol (1S,2S,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol (1R,2S,4R)-borneol AsparagusRoot (2S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol

    Molecular Formula: C10H18O

    Molecular Weight: 154.25

    Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Phytochemicals and Natural Products Functional Chemicals > Cosmetics and Synthetic Ingredients > Active Functional Ingredients Functional Chemicals > Consumer & Industrial Chemicals > Fragrances and Flavors Medicinal Chemistry > Pharmaceutical Excipients > Other Pharmaceutical Excipients

    Product Description:
    (1R,2S,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol, commonly known as (+)-borneol, is a bicyclic monoterpene alcohol with the CAS number 464-43-7. It is the naturally occurring enantiomer of borneol, characterized by its camphor-like odor and crystalline solid form. Structurally, it features a bicyclo[2.2.1]heptane skeleton with three methyl substituents and a hydroxyl group at the C2 position, conferring both lipophilic and hydrophilic properties. In the pharmaceutical domain, (+)-borneol is recognized as an active pharmaceutical ingredient (API) with diverse therapeutic applications. It is widely used in traditional Chinese medicine and modern formulations for its analgesic, anti-inflammatory, and neuroprotective effects. Specifically, it acts as a б░guideб▒ drug to enhance the blood-brain barrier permeability of co-administered agents, making it valuable in treating cerebral ischemia and stroke. It is also employed in topical analgesic preparations for pain relief. In the cosmetics and personal care industry, (+)-borneol serves as a functional active ingredient due to its antimicrobial, cooling, and skin-soothing properties. It is incorporated into formulations for acne treatment, anti-aging products, and skin repair creams. Additionally, it functions as a natural fragrance component in perfumes and aromatherapy products. Its safety profile is well-established, though it should be used within regulated concentrations to avoid skin irritation.
    Physical Properties

    Melting Point: 206-209 °C(lit.)

    Boiling Point: 212°Cat760mmHg

    Flash Point: 65 °C

    Density: 0.992g/cm3

    Safety Information

    Packing Level: III

    Hazard Category: 4.1

    Transport Codes: 1312

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