4-Fluoro-3-nitrobenzoic acid, CAS No. 453-71-4

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

453-71-4

Catalog No. EBD992344

CAS 453-71-4

Name 4-Fluoro-3-nitrobenzoic acid

Get Quote

Basic Information

Synonyms: 1-Fluoro-4-(methylsulfonyl)-2-nitrobenzene 4-fluoro-3-nitrobenzoate TIMTEC-BBSBB008336 RARECHEMALBO0969 3-Nitro-4-fluorobenzoicacid 4-Fluoro-3-nitrobenzoicacid

Molecular Formula: C7H4FNO4

Molecular Weight: 185.11

MDL Number: MFCD00007058

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

Product Description:

3-Nitro-4-fluorobenzoic acid is a benzoic acid derivative substituted with a nitro group at the 3-position and a fluorine atom at the 4-position. It is a solid compound that serves as a versatile aromatic building block in organic synthesis. This compound is primarily utilized as a key pharmaceutical intermediate. Its structure, featuring both an electron-withdrawing nitro group and a fluorine atom, makes it a valuable precursor for the synthesis of various active pharmaceutical ingredients (APIs) and other complex molecules through further functional group transformations, such as reduction of the nitro group to an amine. As a bifunctional synthon containing both a carboxylic acid and a halogen (fluorine), it is also employed in cross-coupling reactions and as a starting material in material science research. It is commercially available from chemical suppliers specializing in fine chemicals and building blocks for medicinal chemistry.

Physical Properties

Melting Point: 123-126 °C(lit.)

Boiling Point: 92°C 15mm

Flash Point: 92°C/15mm

Density: 1.568 g/cm3

Solubility: insoluble

Analytical Data

Appearance: white to light yellow crystal powder