(3R,4R)-N-Boc-3-(benzylamino)-4-hydroxypyrrolidine, CAS No. 429673-83-6

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

429673-83-6

Catalog No. EBD11003

CAS 429673-83-6

Name (3R,4R)-N-Boc-3-(benzylamino)-4-hydroxypyrrolidine

Get Quote

Basic Information

Synonyms: (3R,4R)-3-Hydroxy-4-[(phenylmethyl)amino]-1-pyrrolidinecarboxylicacid1,1-dimethylethylester tert-butyl(3R,4R)-3-(benzylamino)-4-hydroxy-pyrrolidine-1-carboxylate (3R,4R)-tert-Butyl3-(benzylamino)-4-hydroxypyrrolidine-1-carboxylate (3R,4R)-N-Boc-3-(benzylamino)-4-hydroxypyrrolidine

Molecular Formula: C16H24N2O3

Molecular Weight: 292.37

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(3R,4R)-N-Boc-3-benzylamino-4-hydroxypyrrolidine is a chiral pyrrolidine derivative featuring both a Boc-protected amine and a benzylamino substituent on the heterocyclic ring. This compound serves as a versatile and crucial chiral building block in pharmaceutical synthesis. Its primary application is as a key intermediate in the synthesis of complex drug molecules. The specific stereochemistry (3R,4R) and the presence of multiple functional groups make it particularly valuable for constructing active pharmaceutical ingredients (APIs) and other bioactive compounds that require precise three-dimensional structures. It is frequently employed in medicinal chemistry research and process development for target-oriented synthesis. As a functionalized chiral amine, it is a valuable reagent for introducing the pyrrolidine scaffold into larger molecular frameworks, often used in the synthesis of potential therapeutic agents targeting various diseases.

Physical Properties

Boiling Point: 424.6 °C at 760 mmHg

Flash Point: 210.6 °C

Density: 1.16 g/cm3