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    42872-73-1

    Catalog No. EBD21887

    CAS 42872-73-1

    Name 2-Bromo-4-methylbenzonitrile

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    Basic Information

    Synonyms: benzonitrile,2-bromo-4-methyl- 2-Bromo-4-methylbenzonitrile

    Molecular Formula: C8H6BrN

    Molecular Weight: 196.04

    MDL Number: MFCD00158968

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Cyano Compounds

    Product Description:
    2-Bromo-4-methylbenzonitrile is an organic compound featuring both a bromine atom and a cyano group attached to a methyl-substituted benzene ring. It is a white to off-white crystalline solid with a molecular formula of C8H6BrN. This compound is a versatile bifunctional building block in synthetic organic chemistry. Its primary application is as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. The bromine atom serves as a reactive site for cross-coupling reactions (e.g., Suzuki, Heck, or Buchwald-Hartwig couplings), while the cyano group can be transformed into various other functional groups such as carboxylic acids, amides, or tetrazoles. This dual functionality makes it a valuable starting material for constructing heterocyclic systems and functionalized aromatic compounds. The compound is handled as a standard laboratory chemical. It should be stored in a cool, dry place away from strong oxidizing agents. Standard safety precautions for handling halogenated and nitrile-containing compounds should be observed, including the use of appropriate personal protective equipment.
    Physical Properties

    Melting Point: 50-55 °C

    Boiling Point: 292.9 °C at 760 mmHg

    Flash Point: >110 °C

    Density: 1.51 g/cm3

    mg g kg ml l t