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    42732-49-0

    Catalog No. EBD9156

    CAS 42732-49-0

    Name 3-Hydroxy-5-picoline

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    Basic Information

    Synonyms: 3-Hydroxy-5-picoline 5-Methyl-3-hydroxypyridine 3-Hydroxy-5-methylpyridine 5-methylpyridin-3-ol

    Molecular Formula: C6H7NO

    Molecular Weight: 109.13

    MDL Number: MFCD00661297

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers

    Product Description:
    5-Methyl-3-hydroxypyridine is a heterocyclic organic compound featuring a pyridine ring substituted with a methyl group at the 5-position and a hydroxyl group at the 3-position. This structure makes it a versatile building block in organic synthesis, particularly for the construction of more complex nitrogen-containing heterocycles. Its primary industrial application is as a key pharmaceutical intermediate. It serves as a crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs). For instance, it is a fundamental starting material or intermediate in the production of certain cardiovascular drugs and other therapeutic agents that contain a substituted pyridine core. The presence of both the hydroxyl and the nitrogen atom allows for selective functionalization, enabling its incorporation into target molecules. Beyond its role in medicinal chemistry, 5-methyl-3-hydroxypyridine is also utilized as a ligand or a modifier in coordination chemistry and material science research due to its chelating potential. Standard safety precautions for handling organic chemicals should be observed, including the use of personal protective equipment.
    Physical Properties

    Boiling Point: 317.3 °C at 760 mmHg

    Flash Point: 145.7 °C

    Density: 1.12 g/cm3

    Analytical Data

    Appearance: Light yellow cryst

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