Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    425663-71-4

    Catalog No. EBD473205

    CAS 425663-71-4

    Name (1S)-1-amino-3-methyl-1H,4H,5H-benzo[d]azaperhydroepin-2-one hydrochloride

    Get Quote
    Basic Information

    Synonyms: (1S)-1-amino-3-methyl-1H,4H,5H-benzo[d]azaperhydroepin-2-onehydrochloride (S)-1-amino-3-methyl-1,3,4,5-tetrahydrobenz[d]azepin-2-onehydrochloride 2H-3-Benzazepin-2-one,1-amino-1,3,4,5-tetrahydro-3-methyl-,hydrochloride(1:1),(1S)- 2H-3-Benzazepin-2-one,1-amino-1,3,4,5-tetrahydro-3-methyl-,monohydrochloride,(1S)- S-1-aMino-4,5-dihydro-3-Methyl-1H-benzo[d]azepin-2(3H)-one

    Molecular Formula: C11H14N2O*ClH

    Molecular Weight: 226.71

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

    Product Description:
    (1S)-1-amino-3-methyl-1H,4H,5H-benzo[d]azaperhydroepin-2-one hydrochloride is a chiral, heterocyclic organic compound featuring a benzazepinone core structure with an amino group and a methyl substituent. It is a hydrochloride salt, which typically enhances its stability and solubility for pharmaceutical processing. This compound is a key chiral intermediate in the synthesis of Vilazodone, a serotonin reuptake inhibitor and 5-HT1A receptor partial agonist used as an antidepressant. Its specific stereochemistry ((1S)-configuration) is crucial for the biological activity of the final API. The synthesis and supply of this high-purity intermediate are critical steps in the manufacturing process of Vilazodone. As a specialized building block for a specific drug, it is primarily of interest in pharmaceutical research and development, particularly in process chemistry and scale-up for API production. Handling requires standard laboratory precautions for fine chemicals.
    Physical Properties

    Storage: −20°C

    mg g kg ml l t