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    403-19-0

    Catalog No. EBD13337

    CAS 403-19-0

    Name 2-Fluoro-4-nitrophenol

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    Basic Information

    Synonyms: 3-Fluoro-4-chlorobenzoicacid 2-Fluoro-4-nitrophenol Phenol,2-fluoro-4-nitro- 2-fluoro-4-nitrophenolate

    Molecular Formula: C6H4FNO3

    Molecular Weight: 157.1

    MDL Number: MFCD00051970

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers

    Product Description:
    2-Fluoro-4-nitrophenol is an organic compound characterized by a phenol ring substituted with a fluorine atom at the ortho position and a nitro group at the para position. It is a solid at room temperature and serves as a versatile bifunctional building block in synthetic organic chemistry. Its primary utility lies in its role as a key intermediate in the synthesis of more complex molecules. The presence of both an electron-withdrawing nitro group and a reactive phenolic hydroxyl group, along with the fluorine atom which can participate in nucleophilic aromatic substitution (SNAr) reactions, makes it a valuable precursor. It is commonly used in the preparation of dyes, pigments, and various pharmaceutical intermediates. The compound is also employed in the synthesis of liquid crystals and other advanced materials. Handling requires standard precautions for nitroaromatic and phenolic compounds. It should be stored in a cool, dry place away from strong oxidizers and bases.
    Physical Properties

    Melting Point: 120-122 °C(lit.)

    Boiling Point: 281.2 °C at 760 mmHg

    Flash Point: 123.9 °C

    Density: 1.511 g/cm3

    Analytical Data

    Appearance: yellow crystalline powder

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