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    397843-80-0

    Catalog No. EBD15410

    CAS 397843-80-0

    Name (4-Benzamidophenyl)boronic acid

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    Basic Information

    Synonyms: 4-Benzamidophenylboronicacid {4-[(phenylcarbonyl)amino]phenyl}boronicacid (4-Benzamidophenyl)boronicacid

    Molecular Formula: C13H12BNO3

    Molecular Weight: 241.05

    MDL Number: MFCD08235089

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters

    Product Description:
    4-Benzamidophenylboronic acid is an organic compound featuring a boronic acid functional group attached to a phenyl ring, which is further substituted with a benzamide group. This structure makes it a bifunctional building block, combining the reactivity of an arylboronic acid with the hydrogen-bonding and structural features of an amide. Its primary application is in medicinal chemistry and pharmaceutical research as a key synthetic intermediate. The arylboronic acid moiety is widely utilized in Suzuki-Miyaura cross-coupling reactions, a fundamental method for constructing biaryl structures, which are common scaffolds in many drug molecules. The benzamide group can serve as a pharmacophore or a structural linker. This compound is specifically cited in patent literature related to the synthesis of kinase inhibitors and other biologically active small molecules. As a specialized boronic acid derivative, it is not a commodity chemical but a research-grade material used in the discovery and development of new therapeutic agents, particularly in constructing complex molecular architectures for biological screening.
    Physical Properties

    Melting Point: 194-196 °C

    Density: 1.28 g/cm3

    mg g kg ml l t