Boc-Tyr-OH, CAS No. 3978-80-1

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

3978-80-1

Catalog No. EBD2156845

CAS 3978-80-1

Name Boc-Tyr-OH

Get Quote

Basic Information

Synonyms: N-(tert-butoxycarbonyl)tyrosine N-(tert-butoxycarbonyl)-L-tyrosine (2S)-2-[(tert-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoate BOC-L-Tyrosine tert-butoxycarbonyl-tyrosine n-boc-l-tyrosine

Molecular Formula: C14H19NO5

Molecular Weight: 281.3

MDL Number: MFCD00037179

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

Boc-L-Tyrosine is a protected derivative of the essential amino acid L-tyrosine, where the α-amino group is shielded by a tert-butoxycarbonyl (Boc) protecting group. This white to off-white crystalline powder is a crucial building block in peptide synthesis and medicinal chemistry. Its primary application is as a key intermediate in the solid-phase and solution-phase synthesis of peptides and peptidomimetics. The Boc group is stable under many reaction conditions but can be selectively removed under acidic conditions, allowing for the sequential assembly of complex peptide chains. It is extensively used in the research and development of peptide-based pharmaceuticals, including hormone analogs, enzyme inhibitors, and other bioactive molecules. As a derivative of L-tyrosine, it also serves as a precursor for studying tyrosine metabolism and for incorporating the tyrosine moiety into larger biomolecules. It is a standard reagent in biochemical and pharmaceutical laboratories for constructing peptides containing this important aromatic amino acid.

Physical Properties

Melting Point: 133-135 °C(lit.)

Boiling Point: 484.9 °C at 760 mmHg

Flash Point: 247.1 °C

Density: 1.238 g/cm3

Storage: −20°C