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    39546-32-2

    Catalog No. EBD2199459

    CAS 39546-32-2

    Name isonipecotamide

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    Basic Information

    Synonyms: 4-Piperidinecarboxamide 4-carbamoylpiperidinium isonipecotamide Hexahydroisonicotinamide

    Molecular Formula: C6H12N2O

    Molecular Weight: 128.17

    MDL Number: MFCD00038012

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    4-Piperidinecarboxamide is an organic compound featuring a piperidine ring substituted with a carboxamide group at the 4-position. It is a white to off-white crystalline solid. As a heterocyclic amine derivative, it serves as a versatile building block in organic synthesis. Its primary application is in pharmaceutical research and development, where it is used as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). The piperidine scaffold is a privileged structure in medicinal chemistry, found in drugs targeting the central nervous system, as well as in compounds with antimicrobial and other therapeutic activities. The carboxamide group provides a handle for further chemical modifications, making this compound a valuable precursor. While its main use is as a pharmaceutical intermediate, its well-defined structure also makes it a useful starting material or reagent in general synthetic chemistry for constructing more complex nitrogen-containing heterocycles and amide derivatives.
    Physical Properties

    Melting Point: 145-148 °C(lit.)

    Boiling Point: 311.7 °C at 760 mmHg

    Flash Point: 142.3 °C

    Density: 1.06 g/cm3

    Analytical Data

    Appearance: White to light yellow crystalline powder

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