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    3939-09-1

    Catalog No. EBD581063

    CAS 3939-09-1

    Name 2,4-Difluorobenzonitrile

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    Basic Information

    Synonyms: 2,4-Difluorobenzonitrile NCRBFDF

    Molecular Formula: C7H3F2N

    Molecular Weight: 139.1

    MDL Number: MFCD00009826

    Categories: Synthetic Chemistry > Organic Building Blocks > Cyano Compounds Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    2,4-Difluorobenzonitrile is an organic compound featuring a benzene ring substituted with two fluorine atoms at the 2- and 4- positions and a cyano group. It is a colorless to pale yellow liquid or low-melting solid with a molecular formula of C7H3F2N. This compound serves as a versatile and important building block in organic synthesis. The presence of both fluorine atoms and a cyano group makes it a valuable precursor for the synthesis of various heterocyclic compounds, pharmaceuticals, and agrochemicals. The cyano group can be readily transformed into other functional groups such as carboxylic acids, amides, or tetrazoles, while the fluorine atoms can participate in nucleophilic aromatic substitution reactions or influence the electronic properties of the final molecule. It is commonly used in the research and development of active pharmaceutical ingredients (APIs) and advanced materials. As a bifunctional synthon, it is a key intermediate in the preparation of compounds like fluoroquinolone antibiotics and other bioactive molecules where the difluorophenyl moiety is a critical structural element.
    Physical Properties

    Melting Point: 47-49 °C(lit.)

    Boiling Point: 189°C

    Flash Point: 113 °C

    Density: 1.246

    mg g kg ml l t