1-chloro-4-(diethoxyphosphorylmethyl)benzene, CAS No. 39225-17-7

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

39225-17-7

Catalog No. EBD102562

CAS 39225-17-7

Name 1-chloro-4-(diethoxyphosphorylmethyl)benzene

Get Quote

Basic Information

Synonyms: 1-chloro-4-(diethoxyphosphorylmethyl)benzene diethyl4-chlorobenzylphosphonate diethyl(4-chlorobenzyl)phosphonate diethyl(p-chlorobenzyl)phosphonate 4-(chlorobenzyl)phosphonicaciddiethylester p-(chlorobenzyl)phosphonicaciddiethylester [(4-chlorophenyl)methyl]phosphonicaciddiethylester

Molecular Formula: C11H16ClO3P

Molecular Weight: 262.67

MDL Number: MFCD00051568

Categories: Synthetic Chemistry > Organic Building Blocks > Phosphorus Compounds Synthetic Chemistry > Basic Synthetic Reagents > Other Basic Synthetic Reagents

Product Description:

4-Chlorobenzyl diethyl phosphate is an organophosphorus compound characterized by a benzyl phosphate ester structure with a chloro substituent at the para position of the aromatic ring. It serves as a versatile synthetic intermediate and reagent in organic chemistry. Its primary application is as a phosphorylating agent or a protected form of a 4-chlorobenzyl alcohol equivalent in nucleoside and nucleotide chemistry. It is notably used in the synthesis of modified nucleoside monophosphates and dinucleotides, where the phosphate group can be further functionalized. The compound acts as a key building block for introducing the phospho-4-chlorobenzyl moiety, which can be cleaved under specific conditions. This reagent is valuable in the preparation of prodrugs and in constructing complex molecular architectures that require phosphate ester linkages. It is typically handled under inert atmosphere and stored at low temperatures due to its sensitivity to moisture and potential hydrolysis.

Physical Properties

Boiling Point: 162 °C(lit.)

Flash Point: >110 °C

Density: 1.19 g/mL at 25 °C(lit.)

Refractivity: n20/D 1.509(lit.)